Impact of trimethoprim on the river microbiome and antimicrobial resistance.
J. Delaney, S. Raguideau, J. Holden, L. Zhang, H. Tipper, G. Hill, U. Klumper, T. Zhang, R. S. James, E. R. Travis, M. J. Bowes, P. M. Hawkey, H. S. Lindstrom, C. Tang, W. H. Gaze, , E. M. Wellington
This study investigates the relationship between trimethoprim concentrations and antimicrobial resistance gene prevalence in river sites across the Thames catchment, finding significant seasonal and land-use correlations.
bioRxiv · Jun 5, 2020 · PreprintMicrobiology