Author

A. Mead

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Evolutionary Biology· 1 Microbiology· 1 Pathology· 1 Plant Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Organism:human· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Research Focus:ecology & biodiversity· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2

Frequent Co-Authors

N. Sousos· 3 shared B. Psaila· 2 shared D. Royston· 2 shared K. Sirinukunwattana· 2 shared A. Aberdeen· 1 shared A. C. Singer· 1 shared A. Hamblin· 1 shared A. K. Krishnan· 1 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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3 shared papersCancer Biology

N. Sousos

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Comparison of conservation strategies for California Channel Island Oak (Quercus tomentella) using climate suitability predicted from genomic data

A. Mead, S. Fitz-Gibbon, J. Knapp, V. Sork

This study compares conservation strategies for Island Oak using genomic data to predict climate suitability and assess maladaptation risks under different management approaches.

bioRxiv · May 23, 2024Evolutionary Biology

A pro-inflammatory stem cell niche drives myelofibrosis through a targetable galectin 1 axis

R. Li, M. Colombo, G. Wang, A. Rodriguez-Romera, J. O'Sullivan, S.-A. Clark, J. Perez Saez, Y. Meng, A. Khan, S. Wen, P. Dong, W. Zhou, N. Sousos, L. Murphy, M. Clarke, , B. Psaila

This study identifies a pro-inflammatory stem cell niche that drives myelofibrosis via galectin 1, offering a targetable pathway for therapy.

bioRxiv · Aug 5, 2023 · PreprintCancer Biology

Time series transcriptomics reveals a BBX32-directed control of dynamic acclimation to high light in mature Arabidopsis leaves

P. M. Mullineaux, R. Alvarez-Fernandez, C. A. Penfold, G. Galvez-Valdivieso, M. Exposito-Rodriguez, E. J. Stallard, L. Bowden, J. D. Moore, A. Mead, P. Davey, J. S. Matthews, J. Beynon, V. Buchanan-Wollaston, D. L. Wild, T. Lawson, , K. Denby

The paper identifies BBX32 as a key regulator of dynamic acclimation to high light in Arabidopsis by analyzing time-series transcriptomics data and constructing a gene regulatory network.

bioRxiv · Dec 23, 2020 · PreprintPlant Biology

Impact of trimethoprim on the river microbiome and antimicrobial resistance.

J. Delaney, S. Raguideau, J. Holden, L. Zhang, H. Tipper, G. Hill, U. Klumper, T. Zhang, R. S. James, E. R. Travis, M. J. Bowes, P. M. Hawkey, H. S. Lindstrom, C. Tang, W. H. Gaze, , E. M. Wellington

This study investigates the relationship between trimethoprim concentrations and antimicrobial resistance gene prevalence in river sites across the Thames catchment, finding significant seasonal and land-use correlations.

bioRxiv · Jun 5, 2020 · PreprintMicrobiology

Improving the diagnosis and classification of Ph-negative myeloproliferative neoplasms through deep phenotyping

K. Sirinukunwattana, A. Aberdeen, H. Theissen, N. Sousos, B. Psaila, A. Mead, G. Turner, G. Rees, J. Rittscher, D. Royston

This paper develops a machine-learning approach to automate megakaryocyte morphology analysis in bone marrow trephine samples to improve diagnosis of Ph-negative myeloproliferative neoplasms.

bioRxiv · Sep 11, 2019 · PreprintPathology

Heterogeneous disease-propagating stem cells in juvenile myelomonocytic leukemia

E. Louka, B. Povinelli, A. Rodriguez Meira, G. Buck, N. Ashley, A. Hamblin, C. A. G. Booth, N. Sousos, A. Roy, N. Elliott, D. Iskander, J. De la Fuente, N. Fordham, S. O'Byrne, S. Inglott, , A. Mead

This study identifies heterogeneous leukemia stem cells in JMML using single-cell RNA-sequencing and clonogenic assays, revealing their molecular features and potential therapeutic targets.

bioRxiv · May 7, 2019Cancer Biology