Author

H. V. Truong

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:biophysical modeling· 1 Approach:experimental assay· 1 Research Focus:protein folding & dynamics· 1 Research Focus:protein structure prediction· 1 Assay:proteomics· 1 Assay:structural biology· 1

Frequent Co-Authors

M. C. Young· 2 shared N. G. Sgourakis· 2 shared S. Gupta· 2 shared Y. Sun· 2 shared A. Farrel· 1 shared B. R. Kiefel· 1 shared C. H. Woodward· 1 shared E. Mycek· 1 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersBiochemistry

M. C. Young

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2 papers

Recent·Most cited

Structural principles of peptide-centric Chimeric Antigen Receptor recognition guide therapeutic expansion

Y. Sun, T. J. Florio, S. Gupta, M. C. Young, Q. F. Marshall, S. E. Garfinkle, G. F. Papadaki, H. V. Truong, E. Mycek, P. Li, A. Farrel, N. L. Church, S. Jabar, M. D. Beasley, B. R. Kiefel, , N. G. Sgourakis

This paper determines the structure of a peptide-centric Chimeric Antigen Receptor (PC-CAR) complex and identifies structural principles for antigen recognition across multiple HLA allotypes.

bioRxiv · May 24, 2023Biochemistry

Universal open MHC-I molecules for rapid peptide loading and enhanced complex stability across HLA allotypes

Y. Sun, M. C. Young, C. H. Woodward, J. N. Danon, H. V. Truong, S. Gupta, T. J. Winters, G. Burslem, N. G. Sgourakis

This paper introduces engineered MHC-I molecules with enhanced stability and peptide exchange capabilities across multiple HLA allotypes, enabling improved antigen screening and TCR analysis.

bioRxiv · Mar 18, 2023Biochemistry