Author

C. H. Woodward

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:protein folding & dynamics· 2 Approach:biophysical modeling· 1 Organism:chicken / avian· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:protein structure· 1 Assay:proteomics· 1

Frequent Co-Authors

M. C. Young· 2 shared N. G. Sgourakis· 2 shared T. J. Winters· 2 shared G. Burslem· 1 shared G. F. Papadaki· 1 shared G. M. Burslem· 1 shared H. V. Truong· 1 shared J. N. Danon· 1 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersImmunology

M. C. Young

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2 papers

Recent·Most cited

ImmunologybioRxivPreprintJun 23, 2023

A Chicken Tapasin ortholog can chaperone empty HLA molecules independently of other peptide-loading components

G. F. Papadaki, C. H. Woodward, M. C. Young…·N. G. Sgourakis

This study shows that chicken Tapasin can stabilize human HLA molecules without co-chaperones and can bind peptides, suggesting its use in engineering MHC-I ligand exchange.

DOI 10.1101/2023.06.23.546255

chicken / avianprotein structure

𝕏 PostBluesky

BiochemistrybioRxivMar 18, 2023

Universal open MHC-I molecules for rapid peptide loading and enhanced complex stability across HLA allotypes

Y. Sun, M. C. Young, C. H. Woodward…·N. G. Sgourakis

This paper introduces engineered MHC-I molecules with enhanced stability and peptide exchange capabilities across multiple HLA allotypes, enabling improved antigen screening and TCR analysis.

DOI 10.1073/pnas.2304055120

humanproteomics

𝕏 PostBluesky