Author

T. J. Winters

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:protein folding & dynamics· 2 Approach:biophysical modeling· 1 Organism:chicken / avian· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:protein structure· 1 Assay:proteomics· 1

Frequent Co-Authors

C. H. Woodward· 2 shared M. C. Young· 2 shared N. G. Sgourakis· 2 shared G. Burslem· 1 shared G. F. Papadaki· 1 shared G. M. Burslem· 1 shared H. V. Truong· 1 shared J. N. Danon· 1 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersImmunology

C. H. Woodward

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2 papers

Recent·Most cited

A Chicken Tapasin ortholog can chaperone empty HLA molecules independently of other peptide-loading components

G. F. Papadaki, C. H. Woodward, M. C. Young, T. J. Winters, G. M. Burslem, N. G. Sgourakis

This study shows that chicken Tapasin can stabilize human HLA molecules without co-chaperones and can bind peptides, suggesting its use in engineering MHC-I ligand exchange.

bioRxiv · Jun 23, 2023 · PreprintImmunology

Universal open MHC-I molecules for rapid peptide loading and enhanced complex stability across HLA allotypes

Y. Sun, M. C. Young, C. H. Woodward, J. N. Danon, H. V. Truong, S. Gupta, T. J. Winters, G. Burslem, N. G. Sgourakis

This paper introduces engineered MHC-I molecules with enhanced stability and peptide exchange capabilities across multiple HLA allotypes, enabling improved antigen screening and TCR analysis.

bioRxiv · Mar 18, 2023Biochemistry