Visualizing cancer-originated acetate uptake through MCT1 in reactive astrocytes demarcates tumor border and extends survival in glioblastoma patients
H. Y. Ko, J.-I. Chung, D. Kim, Y. M. Park, H. H. Jo, S. Lee, S. Y. Kim, J. Kim, J.-H. Chun, K.-S. Han, M. Lee, Y. Ju, S. J. Park, K. D. Park, M.-H. Nam, , M. Yun
This study uses AcePET to visualize tumor boundaries and reactive astrocytes in GBM, showing that targeting MCT1 improves survival by enabling complete resection of cancer stem cells.
bioRxiv · Apr 13, 2021 · PreprintCancer Biology