Author

H. Zschach

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:deep learning· 2 Assay:protein structure· 2 Approach:statistical model· 2 Research Focus:variant effect prediction· 2 Assay:bulk RNA-seq· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

A. Stein· 2 shared K. Lindorff-Larsen· 2 shared A. G. Gheorghe· 1 shared A. Valanciute· 1 shared B. G. Fritz· 1 shared H. Raskov· 1 shared I. Gogenur· 1 shared J. K. Tiemann· 1 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersBiophysics

A. Stein

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Biofilms and core pathogens shape the tumour microenvironment and immune phenotype in colorectal cancer

L. Kvich, B. G. Fritz, H. Zschach, T. Terkelsen, H. Raskov, K. Hoest-Rasmussen, M. R. Jakobsen, A. G. Gheorghe, I. Gogenur, T. Bjarnsholt

The paper investigates how biofilms and core pathogens like Bacteroides fragilis and Fusobacterium nucleatum influence the tumor microenvironment and immune phenotype in colorectal cancer.

bioRxiv · Oct 20, 2023 · PreprintCancer Biology

Accurate protein stability predictions from homology models

A. Valanciute, L. Nygaard, H. Zschach, M. M. Jepsen, K. Lindorff-Larsen, A. Stein

This study evaluates the accuracy of protein stability predictions from homology models compared to crystal structures, finding they perform equally well when sequence identity is at least 40%.

bioRxiv · Jul 12, 2022Biophysics

Interpreting the molecular mechanisms of disease variants in human membrane proteins

J. K. Tiemann, H. Zschach, K. Lindorff-Larsen, A. Stein

This paper investigates missense variants in human membrane proteins, finding that loss of stability is a common mechanism for pathogenicity in over half of the studied variants.

bioRxiv · Jul 12, 2022Biophysics