Author

H.-Y. Lim

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Organism:plant (other)· 1 Research Focus:protein design· 1 Assay:protein structure· 1 Approach:statistical model· 1

Frequent Co-Authors

B. Guan· 1 shared C. T. Pierce· 1 shared G. Casadevall· 1 shared H. Aihara· 1 shared I. Rus· 1 shared J. Iglesias-Fernandez· 1 shared K. Shi· 1 shared L. R. Greenberg· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperBioengineering

B. Guan

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Author profile →

2 papers

Recent·Most cited

Designing Efficient Enzymes: Eight Predicted Mutations Convert a Hydroxynitrile Lyase into an Efficient Esterase

G. Casadevall, C. T. Pierce, B. Guan, J. Iglesias-Fernandez, H.-Y. Lim, L. R. Greenberg, M. E. Walsh, K. Shi, W. R. Gordon, H. Aihara, R. L. Evans, R. J. Kazlauskas, S. Osuna

The paper identifies eight mutations that convert a hydroxynitrile lyase into an efficient esterase by correcting structural differences using shortest path maps.

bioRxiv · Aug 23, 2023 · PreprintBioengineering

Inhibition of inositol-requiring enzyme 1 RNase activity protects pancreatic beta cell and improves diabetic condition in insulin mutation-induced diabetes

O. Herlea-Pana, V. Eeda, R. Undi, I. Rus, H.-Y. Lim, W. Wang

This study shows that inhibiting IRE1 RNase activity protects beta cells and improves diabetes in Akita mice with insulin mutation-induced diabetes.

bioRxiv · Aug 30, 2020 · PreprintPharmacology & Toxicology