Synaptic Dysfunction and Compensation After NMDA Receptor Ablation in the Mouse Medial Prefrontal Cortex
Rachel M. Dick, Lydia B Cunitz, Alina Pérez, Habsa Ahmed, Anisha P Adke, Cristina Rivera Quiles, Jason S. Mitchell, Ezequiel Marrón Fernández de Velasco, Nicola M. Grissom, Patrick E. Rothwell
This study investigates how NMDAR ablation in adolescent mice affects synaptic structure and function in the medial prefrontal cortex, revealing early disruption followed by compensatory recovery.
bioRxiv · Aug 14, 2025 · PreprintNeuroscience