Molecular profiling of retinal pigment epithelial cell differentiation for therapeutic use
Sandra Petrus-Reurer, Alex R. Lederer, Laura Baqué-Vidal, Iyadh Douagi, Belinda Pannagel, Monica Aronsson, Hammurabi Bartuma, Magdalena Wagner, Helder André, Erik Sundström, Aparna Bhaduri, Arnold R. Kriegstein, Anders Kvanta, Gioele La Manno, Fredrik Lanner
This study maps the single-cell transcriptomic dynamics of hESC-RPE differentiation, identifies an intermediate progenitor, and shows in vivo maturation after transplantation.
bioRxiv · Jan 31, 2021 · PreprintDevelopmental Biology