Genetic variation in activating clopidogrel: longer-term outcomes in a large community cohort
Luke C. Pilling, Deniz Türkmen, Hannah Fullalove, Janice L. Atkins, João Delgado, Chia‐Ling Kuo, George A. Kuchel, Luigi Ferrucci, Jack Bowden, Jane A. H. Masoli, David R. Melzer
This study finds that CYP2C19 loss-of-function variants are associated with increased risk of ischemic stroke and MI in patients on long-term clopidogrel therapy in primary care.
BMJ Open · Dec 1, 2021Peer-reviewedGenetic & Genomic Medicine