Mucin-binding protein shuttles enable delivery of brain-targeted therapeutics
Sophia M. Shi, Gabrielle S. Tender, Jian Xiong, Josephine K. Buff, Hannah I. Park, Justin H. Mendiola, Edward N. Wilson, Monther Abu-Remaileh, Carolyn Ruth Bertozzi, Tony Wyss‐Coray
The paper introduces GlycoShuttles, mucin-binding protein shuttles that deliver therapeutics across the blood-brain barrier into brain cells, showing efficacy in dementia models.
bioRxiv · Apr 12, 2026 · PreprintNeuroscience