Integrase-On-Demand: Bioprospecting integrases for targeted genomic insertion of genetic cargo
Hannah M. McClain, Lillian C Lowrey, Laura B Quinto, Ellis L. Torrance, Tomas R Gagliano, Farren J. Isaacs, Joseph S. Schoeniger, Kelly Porter Williams, Catherine M. Mageeney
The paper introduces Integrase-On-Demand (IOD), a method to identify integrases from bacteria and archaea that can integrate genetic cargo into target prokaryotes without requiring synthetic attB sites.
Nucleic Acids Research · Jan 29, 2026Peer-reviewedSynthetic Biology