Catherine M. Mageeney

This study identifies eight cytotoxic genes in a Pseudomonas putida phage through genome-wide overexpression, revealing metabolic remodeling and conserved proteins across diverse phages.

The paper investigates how different chemical stressors induce prophage replication in Acinetobacter baumannii strains, revealing differential induction patterns across host backgrounds.

The paper examines GI activity in a microbial consortium under stress, finding increased excision and expression compared to monocultures, and highlights the importance of community context in GI dynamics.

The paper identifies a novel phage resistance mechanism in Pseudomonas putida through experimental evolution, revealing a secreted protein Psh that confers broad-spectrum phage resistance without fitness costs.

The paper identifies and characterizes prophages in A. baumannii isolates using computational analysis and experimental induction, showing their potential as therapeutic agents against antibiotic-resistant strains.

The paper introduces HtPIP, a high-throughput phage isolation platform that increases diversity and reduces isolation time by isolating novel phages from environmental samples.

The paper introduces Integrase-On-Demand (IOD), a method to identify integrases from bacteria and archaea that can integrate genetic cargo into target prokaryotes without requiring synthetic attB sites.

This study shows that probiotic communities can prevent Burkholderia thailandensis infection in mice by reducing niche overlap with the pathogen.

The paper characterizes novel recombinant mycobacteriophages generated through homologous recombination between two temperate phages, showing they are homoimmune to Island3 and can overcome antiphage defenses.

The paper identifies helper-embedded satellites (HESs) that integrate into prophage late genes, revealing a new cis-regulatory mechanism and genomic organization.

The paper reports the draft genome sequences of three Burkholderia thailandensis strains, providing their contig counts, lengths, and GC content.

The paper introduces TIGER, a software tool that precisely maps integrative genetic elements, revealing 19 new cases of gene integrity regulation by IGEs.