Kelly Porter Williams

The paper identifies temperature-responsive integrases from extremophiles and demonstrates their use in creating temperature-switchable genome editing systems.

The paper examines GI activity in a microbial consortium under stress, finding increased excision and expression compared to monocultures, and highlights the importance of community context in GI dynamics.

The paper introduces Integrase-On-Demand (IOD), a method to identify integrases from bacteria and archaea that can integrate genetic cargo into target prokaryotes without requiring synthetic attB sites.

RNAcentral integrates literature and gene-level data to enhance non-coding RNA sequence analysis and functional understanding.

This study shows that probiotic communities can prevent Burkholderia thailandensis infection in mice by reducing niche overlap with the pathogen.

EMMA adds unaligned sequences to a constraint alignment with high accuracy and scalability for large datasets.

The paper identifies helper-embedded satellites (HESs) that integrate into prophage late genes, revealing a new cis-regulatory mechanism and genomic organization.

SALMA improves multiple sequence alignment accuracy and scalability for large datasets with high evolutionary rates and sequence length variation.

The paper reports the draft genome sequences of three Burkholderia thailandensis strains, providing their contig counts, lengths, and GC content.

The paper introduces TIGER, a software tool that precisely maps integrative genetic elements, revealing 19 new cases of gene integrity regulation by IGEs.

The paper develops a software module to precisely map group I introns in bacterial tRNA genes, expanding known intron types from four to 21.