PDLIM5 Modulates YAP1 Localisation and Fibrogenic Gene Expression in Hepatic Stellate Cells
Kara Simpson, Dina I. Abdelmottaleb, Lana Ibrahim, Elliot Jennings, Hayato Kakinuma, Joel Malungu Makopa, Anna Meier, Rabea Pätzold, Lindsay Birchall, Varinder Singh Athwal, Elliot J. Jokl, Tristan R. McKay, Karen Piper Hanley, Jonathan D. Humphries, J.P. Pritchett
This study shows that PDLIM5 regulates YAP1 localization and fibrogenic gene expression in hepatic stellate cells through mechanical cues.
bioRxiv · Sep 28, 2026 · PreprintCell Biology