Kara Simpson

This study shows that PDLIM5 regulates YAP1 localization and fibrogenic gene expression in hepatic stellate cells through mechanical cues.

This study shows that SOX9 is critical for maintaining granuloma structure and ECM barrier formation in schistosomiasis, which protects the liver from damage.

The paper maps the spatial transcriptional changes in human liver cirrhosis, identifying gene signatures and cell state transitions linked to disease progression.