Discovery of non-opioid receptor protein targets of fentanyl across tissues from animal models and humans using photoaffinity probes
Vivian Lin, Kiall F. Suazo, Doo Nam Kim, Damon T. Leach, Agne Sveistyte, Jennifer Walker, Leo J. Gorham, Katherine Schultz, Kai‐For Mo, Stephen Callister, Kelly G. Stratton, Gerard X. Lomas, William C. Nelson, Heather A. Colburn, Vanessa Paurus, , Aaron Wright
This study identifies non-opioid receptor proteins that interact with fentanyl across multiple species and tissues using photoaffinity probes and molecular docking.
bioRxiv · Feb 20, 2025 · PreprintPharmacology & Toxicology