Astrocytic Slc4a4 regulates blood-brain barrier integrity in healthy and stroke brains via a NO-CCL2-CCR2 pathway
Qi Ye, Juyeon Jo, Chih‐Yen Wang, Heavin Oh, Tiffany J. Choy, Kyoungin Kim, Angelo D’Alessandro, Yana K. Reshetnyak, Sung Yun Jung, Zheng Chen, Sean P. Marrelli, Hyun Kyoung Lee
This study identifies Slc4a4's role in maintaining blood-brain barrier integrity through the NO-CCL2-CCR2 pathway in astrocytes, showing its importance in both healthy and stroke conditions.
bioRxiv · Apr 3, 2023 · PreprintNeuroscience