Neurons from individual early Alzheimer's disease patients reflect clinical vulnerability
Bryan Ng, Helen A Rowland, Liting Wei, Kanisa Arunasalam, Emma Mee Hayes, Ivan G. Koychev, Anne Hedegaard, Elena M. Ribé, Dennis Chan, Tharani Chessell, Dominic H Ffytche, Roger N. Gunn, Ece Kocagöncü, Jennifer Lawson, Paresh Malhotra, , Richard Wade‐Martins
The paper uses induced pluripotent stem cell-derived cortical neurons from early Alzheimer's patients to show that cellular vulnerability to amyloid-beta correlates with clinical vulnerability.
Brain Communications · Oct 20, 2022Peer-reviewedNeuroscience