Author

Paresh Malhotra

Imperial College LondonORCID 0000-0002-1897-0780Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Organism:human· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Assay:imaging· 1 Assay:scRNA-seq· 1 Approach:simulation· 1

Frequent Co-Authors

Dennis ChaniD· 3 shared Ivan G. KoycheviD· 3 shared Alan J. ThomasiD· 2 shared Anne HedegaardiD· 2 shared Basil H. RidhaiD· 2 shared Bryan NgiD· 2 shared Ece KocagöncüiD· 2 shared Elena M. RibéiD· 2 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersNeuroscience

Dennis ChanORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

iPSC-Astrocyte morphology reflects patient clinical markers

Helen A. Rowland, Georgina Miller, Qiang Liu, Nicola R Sharp, Bryan Ng, Liting Wei, Kanisa Arunasalam, Ivan G. Koychev, Anne Hedegaard, Elena M. Ribé, Dennis Chan, Tharani Chessell, Ece Kocagöncü, Jennifer Lawson, Paresh Malhotra, , Noel J. Buckley

This study shows iPSC-derived astrocytes from AD patients reflect key pathophysiological features, offering a new model for AD research and therapeutic screening.

bioRxiv · Jul 15, 2023 · PreprintNeuroscience

Path integration selectively predicts midlife risk of Alzheimer's disease

Coco Newton, Marianna Pope, Catarina Rua, Richard N. Henson, Zilong Ji, Neil Burgess, Christopher T. Rodgers, Matthias Stangl, Maria‐Eleni Dounavi, Andrea Castegnaro, Ivan G. Koychev, Paresh Malhotra, Thomas Wolbers, Karen A. Ritchie, Craig William Ritchie, , Dennis Chan

The paper shows that midlife path integration impairments predict Alzheimer's disease risk, independent of other cognitive tests.

bioRxiv · Jan 31, 2023 · PreprintNeuroscience

Neurons from individual early Alzheimer's disease patients reflect clinical vulnerability

Bryan Ng, Helen A Rowland, Liting Wei, Kanisa Arunasalam, Emma Mee Hayes, Ivan G. Koychev, Anne Hedegaard, Elena M. Ribé, Dennis Chan, Tharani Chessell, Dominic H Ffytche, Roger N. Gunn, Ece Kocagöncü, Jennifer Lawson, Paresh Malhotra, , Richard Wade‐Martins

The paper uses induced pluripotent stem cell-derived cortical neurons from early Alzheimer's patients to show that cellular vulnerability to amyloid-beta correlates with clinical vulnerability.

Brain Communications · Oct 20, 2022Peer-reviewedNeuroscience