BiochemistrybioRxivPreprint
WDR76 promotes MLL-rearranged leukemia via selective recognition of 5-hydroxymethylcytosine in DNA
Kathryn E. Malecek, Hengyou Weng, Matthew A. Sullivan…·Alexander J. Ruthenburg
This study identifies WDR76 as a hmC-specific protein that promotes MLL-rearranged leukemia by modulating gene expression and facilitating leukemogenesis.