Longitudinally cultured precision cut lung slices as a predictive ex vivo model for lung cancer
Ara Sargsian, Hermon Girmatsion, Vincent Lenders, Bart Ghesquière, Camila Takeno Cologna, Stefaan J. Soenen, Bella B. Manshian
This study validates Precision Cut Lung Slices (PCLS) as an ex vivo model for lung cancer research, showing comparable drug efficacy to in vivo models and potential to reduce animal testing.
Nanomedicine · Jul 20, 2026Peer-reviewedCancer Biology