Stefaan J. Soenen

This study validates Precision Cut Lung Slices (PCLS) as an ex vivo model for lung cancer research, showing comparable drug efficacy to in vivo models and potential to reduce animal testing.

This study shows chemotherapy induces a Wnt-active diapause-DTP state in breast cancer cells, which can be targeted by combined Wnt and chemotherapy inhibition.

This study shows that silver nanoparticles induce immunogenic cell death, enhancing immunotherapy effectiveness by promoting immune cell infiltration and tumor response to checkpoint inhibitors.