Targeting of the nuclear RNA exosome to chromatin by HP1 affects the transcriptional programs of liver cells.
Hiba Souaifan, Mickaël Costallat, Laura Sitkiewicz, Kylian Godest, Florence M. Cammas, Carl Mann, Christian Muchardt, Christophe Rachez
This study shows that HP1 interacts with the RNA exosome, affecting RNA degradation and transcriptional programs in liver cells, with implications for cancer biology.
Nature Communications · Apr 29, 2026Peer-reviewedMolecular Biology