Dynamics and activation of the Legionella Type IV secretion system
Samira Heydari, Jian Yue, Zi Yang, Sheng Shu, Hongpeng Wang, Wei Mi, Craig R. Roy, Jun Liu
This study uses cryo-EM to reveal the structural dynamics and activation mechanism of the Legionella Dot/Icm T4SS, showing how it transitions from a resting state to an active secretion machine.
bioRxiv · Oct 21, 2026 · PreprintMicrobiology