Samira Heydari

This study uses cryo-EM to reveal the structural dynamics and activation mechanism of the Legionella Dot/Icm T4SS, showing how it transitions from a resting state to an active secretion machine.

This paper models the Shigella T3SS pod complex using AlphaFold, showing two Spa33 proteins bind MxiK and SPOA2-SPOA2 domains, supporting a 1:4:2 stoichiometry and explaining electron density data.

This study determines the near-atomic structure of H. pylori sheathed flagella using cryo-EM, revealing how flagellins and glycans contribute to filament stability and motility.

This study uses cryo-electron microscopy to reveal the structure of the Dot/Icm T4SS in Legionella pneumophila, identifying the DotA-IcmX complex as the gatekeeper for effector translocation.