Highly selective SGLT2 inhibitors suppress glucose uptake in alpha-TC1 cells, while glucagon secretion is not affected.
Licht Miyamoto, Suguru Nakayama, Honoka Endoh, Kano Fujiwara, Mana Hattori, Takashi Yasuoka, Masaki Imanishi, Yasumasa Ikeda, Koichiro Tsuchiya
This study investigates the effects of SGLT2 inhibitors on glucose uptake and glucagon secretion in alpha-TC1 cells, finding that SGLT2 mediates basal glucose uptake but not glucagon secretion.
HORMONES · Jul 8, 2026Peer-reviewedPharmacology & Toxicology