Dual profiling of DNA modifications with enhancer features during the exit of naive pluripotency
Marlet Morales-Franco, Baptiste Demaret, Pol Arnau-Romero, Hortense Bouvier, Julien Richard Albert, Aaron Bogutz, Angélique David, Pierre‐Antoine Defossez, Anaïs F. Bardet, Priscillia Lhoumaud, Max Greenberg
The paper uses Methyl-ATAC and Methyl-CUT&Tag to study 5mC and 5hmC dynamics during mESC differentiation, revealing their role in enhancer regulation.
bioRxiv · Aug 15, 2026 · PreprintMolecular Biology