Author

Hrishabh Singh

Yale University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Organism:human· 1 Approach:machine learning (classical)· 1 Approach:mechanistic / dynamical model· 1 Assay:protein structure· 1 Approach:statistical model· 1

Frequent Co-Authors

Debdas DhabaliD· 1 shared Keshav PatiliD· 1 shared Krishna SureshiD· 1 shared Kumar Dilip AshtekariD· 1 shared Mark A. LemmoniD· 1 shared Ravi RadhakrishnaniD· 1 shared Yuko TsutsuiiD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 21 mutual co-author links

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1 shared paperBiophysics

Debdas DhabalORCID

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1 paper

Recent·Most cited

Coupled Solvent and Protein Dynamics Confer Differences in Exon-19 Deletion Mutants of the Epidermal Growth Factor Receptor Kinase

Keshav Patil, Debdas Dhabal, Kumar Dilip Ashtekar, Yuko Tsutsui, Krishna Suresh, Hrishabh Singh, Mark A. Lemmon, Ravi Radhakrishnan

This study identifies two mutation profiles in EGFR Exon-19 deletions that correlate with differential TKI sensitivity through analysis of conformational dynamics and solvent interactions.

bioRxiv · Oct 4, 2024 · PreprintBiophysics