Author

Keshav Patil

University of PennsylvaniaORCID 0000-0003-1722-9314Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Organism:human· 1 Approach:machine learning (classical)· 1 Approach:mechanistic / dynamical model· 1 Assay:protein structure· 1 Approach:statistical model· 1

Frequent Co-Authors

Debdas DhabaliD· 1 shared Hrishabh Singh· 1 shared Krishna SureshiD· 1 shared Kumar Dilip AshtekariD· 1 shared Mark A. LemmoniD· 1 shared Ravi RadhakrishnaniD· 1 shared Yuko TsutsuiiD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

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7 top collaborators · 21 mutual co-author links

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1 shared paperBiophysics

Debdas DhabalORCID

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1 paper

Recent·Most cited

BiophysicsbioRxivPreprintOct 4, 2024

Coupled Solvent and Protein Dynamics Confer Differences in Exon-19 Deletion Mutants of the Epidermal Growth Factor Receptor Kinase

Keshav Patil, Debdas Dhabal, Kumar Dilip Ashtekar…·Ravi Radhakrishnan

This study identifies two mutation profiles in EGFR Exon-19 deletions that correlate with differential TKI sensitivity through analysis of conformational dynamics and solvent interactions.

DOI 10.1101/2024.10.04.616731

humanprotein structure

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