Observing biological spatio-angular structures and dynamics with statistical image reconstruction and polarized fluorescence microscopy
Junyu Liu, Talon Chandler, Yue Li, Atharva Agashe, Mingzhe Wei, Yijun P. Su, Yicong Wu, Tobias I. Baskin, Valentin Jaumouillé, Jiji Chen, Pengcheng Xu, Huihui Ye, Wentao Zhu, Robert S Fischer, Vinay Swaminathan, , Min Yi Guo
This paper introduces an algorithm to reconstruct 3D molecular orientation and density from polarized fluorescence microscopy data, demonstrating its application on biological structures and dynamics.
bioRxiv · Sep 23, 2025 · PreprintBioengineering