Amrinder S. Nain

β4-integrins safeguard nuclear mechanics to suppress prostate cancer progression

This study identifies β4-integrins as critical for maintaining nuclear mechanics and integrity in prostate cancer, linking cell-ECM adhesion to genome stability and patient survival.

Observing biological spatio-angular structures and dynamics with statistical image reconstruction and polarized fluorescence microscopy

This paper introduces an algorithm to reconstruct 3D molecular orientation and density from polarized fluorescence microscopy data, demonstrating its application on biological structures and dynamics.

Confinement in fibrous environments positions and orients mitotic spindles

This study investigates how ECM-confinement affects mitotic spindle positioning and orientation through mechanical interactions and RF patterning.

Three-dimensional spatio-angular fluorescence microscopy with a polarized dual-view inverted selective-plane illumination microscope (pol-diSPIM)

The paper introduces a polarized dual-view light-sheet microscope to recover 3D orientations and positions of fluorescent dipoles, validated with experiments on biological samples.