TAK1 integrates the NLRP1 inflammasome into the innate immune response to double-stranded RNA
Miles R. Corley, Ayumu Hyodo, Hunter C Toyoda, Marisa A. Yonemitsu, Amandine Chantharath, Jennifer Hyde, Patrick S. Mitchell
This study shows TAK1 activates the NLRP1 inflammasome in response to dsRNA, linking it to inflammatory responses in viral infection and autoimmunity.
bioRxiv · Jan 25, 2026 · PreprintImmunology