Author

I. B. Breinyn

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 2 Biophysics· 2

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 3 Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Research Focus:development & morphogenesis· 2 Assay:bulk RNA-seq· 1 Research Focus:clustering· 1 Assay:electrophysiology· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

D. J. Cohen· 4 shared A. E. Wolf· 1 shared A. Martinez-Calvo· 1 shared G. Shim· 1 shared K. Suh· 1 shared M. A. Heinrich· 1 shared R. E. Baker· 1 shared S. F. Martina-Perez· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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4 shared papersBiophysics

D. J. Cohen

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Spatial heterogeneity in collective electrotaxis: continuum modelling and applications to optimal control

S. F. Martina-Perez, I. B. Breinyn, D. J. Cohen, R. E. Baker

This study develops a continuum model to explain spatial velocity heterogeneity in collective electrotaxis and applies it to design electric field protocols for controlled tissue migration.

bioRxiv · Feb 28, 2024 · PreprintBiophysics

E-cadherin biointerfaces reprogram collective cell migration and cell cycling by forcing homeostatic conditions

K. Suh, Y. K. Cho, I. B. Breinyn, D. J. Cohen

This study shows E-cadherin surfaces alter collective cell migration and cell cycling by creating homeostatic conditions through hybrid junctions and reduced focal adhesions.

bioRxiv · Jul 25, 2023 · PreprintBioengineering

Pump it up: bioelectric stimulation controls tissue shape and size

G. Shim, I. B. Breinyn, A. Martinez-Calvo, D. J. Cohen

This study shows that electrical stimulation can rapidly inflate hollow epithelial tissues by creating ion gradients and osmotic pressure, leading to significant changes in tissue volume and shape.

bioRxiv · Nov 22, 2022 · PreprintBioengineering

Short-term stimulation of collective cell migration in tissues reprograms long-term supracellular dynamics

A. E. Wolf, M. A. Heinrich, I. B. Breinyn, T. J. Zajdel, D. J. Cohen

This study shows that short-term bioelectric stimulation of tissue migration reprograms long-term supracellular dynamics, leading to a new migratory state beyond the stimulus.

bioRxiv · Jul 27, 2021Biophysics