Y. K. Cho

E-cadherin biointerfaces reprogram collective cell migration and cell cycling by forcing homeostatic conditions

This study shows E-cadherin surfaces alter collective cell migration and cell cycling by creating homeostatic conditions through hybrid junctions and reduced focal adhesions.

Targeted degradation of microtubule-associated protein tau using an engineered nanobody-E3 ubiquitin ligase adapter fusion

This paper demonstrates that an engineered nanobody-E3 ubiquitin ligase adapter fusion can effectively degrade tau in mouse neurons by leveraging nuclear proteasomal activity.

Yeast biopanning for detecting antibody binding to site-specific phosphorylations in tau

This paper develops a yeast biopanning platform to identify phospho-site specific antibodies against tau, demonstrating robust detection of phosphorylated tau peptides.

Degradation-driven protein level oscillation in the yeast Saccharomyces cerevisiae

This study shows that protein level oscillations in yeast can be controlled by modulating degradation rates, independent of transcription rates.

Yeast surface display of full-length human microtubule-associated protein tau

This study demonstrates that full-length human tau can be displayed on yeast surface, enabling analysis of its conformational changes and interactions without phosphorylation observed in Alzheimer's disease.