Author

I. Eckerle

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Assay:bulk RNA-seq· 2 Organism:human· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:rat· 1

Frequent Co-Authors

C. Alvarez· 2 shared K. Adea· 2 shared L. Kaiser· 2 shared M. Bekliz· 2 shared M. Essaidi-Laziosi· 2 shared P. Sattonnet-Roche· 2 shared A. Kipar· 1 shared C. Drosten· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 34 mutual co-author links

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2 shared papersMicrobiology

C. Alvarez

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Author profile →

3 papers

Recent·Most cited

Immune escape and replicative capacity of Omicron lineages BA.1, BA.2, BA.5.1, BQ.1, XBB.1.5, EG.5.1 and JN.1.1

M. Bekliz, M. Essaidi-Laziosi, K. Adea, K. Hosszu-Fellous, C. Alvarez, M. Bellon, P. Sattonnet-Roche, O. Puhach, D. Dbeissi, M. E. Zaballa, S. Stringhini, I. Guessous, P. Vetter, C. S. Eberhardt, L. Kaiser, I. Eckerle

This study evaluates immune escape and replicative capacity of Omicron variants in human airway epithelial cells and sera from diverse immunological backgrounds.

bioRxiv · Feb 14, 2024 · PreprintMicrobiology

Distinct phenotype of SARS-CoV-2 Omicron BA.1 in human primary cells but no increased host range in cell lines of putative mammalian reservoir species

M. Essaidi-Laziosi, F. J. Perez Rodriguez, C. Alvarez, P. Sattonnet-Roche, G. Torriani, M. Bekliz, K. Adea, M. Lenk, W. Preiser, T. Suliman, M. A. Muller, C. Drosten, L. Kaiser, I. Eckerle

The paper compares the replicative capacity of SARS-CoV-2 variants in human primary cells and mammalian cell lines, finding Omicron BA.1 has a distinct phenotype in human nasal epithelia but no increased host range in other species.

bioRxiv · Oct 4, 2022Microbiology

A novel experimental system reveals immunoregulatory responses as mediators of persistent orthohantavirus infections in a rodent reservoir host

T. Strandin, T. Smura, P. Ahola, K. Aaltonen, T. Sironen, J. Hepojoki, I. Eckerle, R. Ulrich, O. Vapalahti, A. Kipar, K. Forbes

This study develops an experimental system to investigate immunoregulatory responses in bank voles infected with PUUV, revealing that virus-induced interleukin-10 promotes persistent infections by suppressing immune responses.

bioRxiv · Nov 5, 2019 · PreprintMicrobiology