Author

M. A. Muller

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:drug response / drug discovery· 2 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

C. Drosten· 3 shared A. Richter· 2 shared D. Niemeyer· 2 shared N. Heinemann· 2 shared A. Pich· 1 shared B. Mhlekude· 1 shared B. Muhlemann· 1 shared C. Alvarez· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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3 shared papersMicrobiology

C. Drosten

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Author profile →

3 papers

Recent·Most cited

Distinct phenotype of SARS-CoV-2 Omicron BA.1 in human primary cells but no increased host range in cell lines of putative mammalian reservoir species

M. Essaidi-Laziosi, F. J. Perez Rodriguez, C. Alvarez, P. Sattonnet-Roche, G. Torriani, M. Bekliz, K. Adea, M. Lenk, W. Preiser, T. Suliman, M. A. Muller, C. Drosten, L. Kaiser, I. Eckerle

The paper compares the replicative capacity of SARS-CoV-2 variants in human primary cells and mammalian cell lines, finding Omicron BA.1 has a distinct phenotype in human nasal epithelia but no increased host range in other species.

bioRxiv · Oct 4, 2022Microbiology

Pharmacological inhibition of bromodomain and extra-terminal proteins induces NRF-2-mediated inhibition of SARS-CoV-2 replication and is subject to viral antagonism

B. Mhlekude, D. Postmus, J. Weiner, S. Stenzel, F. J. Zapatero-Belinchon, R. Olmer, J. Jansen, A. Richter, J. Heinze, N. Heinemann, B. Muhlemann, S. Schroeder, T. C. Jones, M. A. Muller, C. Drosten, , C. Goffinet

This study shows JQ-1 inhibits SARS-CoV-2 replication via NRF-2 activation but is counteracted by viral antagonism, leading to transient antiviral effects.

bioRxiv · Sep 22, 2022 · PreprintMicrobiology

Analysis of SARS-CoV-2-controlled autophagy reveals spermidine, MK-2206, and niclosamide as putative antiviral therapeutics

N. C. Gassen, J. Papies, T. Bajaj, F. Dethloff, J. Emanuel, K. Weckmann, D. E. Heinz, N. Heinemann, M. Lennarz, A. Richter, D. Niemeyer, V. M. Corman, P. Giavalisco, C. Drosten, M. A. Muller

This study identifies spermidine, MK-2206, and niclosamide as potential antiviral therapeutics by enhancing autophagy against SARS-CoV-2 in vitro.

bioRxiv · Apr 15, 2020Microbiology