Author

I. Esposito

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

A. Baluapuri· 1 shared A. Illendula· 1 shared A. Kahler· 1 shared A. Schramm· 1 shared A. T. den Dekker· 1 shared B. Rotblat· 1 shared C. Funk· 1 shared D. Picard· 1 shared

Activity by Year

2021-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperCancer Biology

A. Baluapuri

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2 papers

Recent·Most cited

EIF4EBP1 is transcriptionally upregulated by MYCN and associates with poor prognosis in neuroblastoma

K. Voeltzke, K. Scharov, C. Funk, A. Kahler, D. Picard, L. Hauffe, M. F. Orth, M. Remke, I. Esposito, T. Kirchner, A. Schramm, B. Rotblat, T. G. P. Gruenewald, G. Reifenberger, G. Leprivier

This study shows EIF4EBP1 is upregulated by MYCN and linked to poor prognosis in neuroblastoma, with high expression associated with reduced survival and unfavorable histology.

bioRxiv · Dec 8, 2021Cancer Biology

NOXA expression drives synthetic lethality to RUNX1 inhibition in pancreatic cancer

J. Doffo, S. A. Bamopoulos, H. Kose, F. Orben, M. Pons, A. T. den Dekker, R. W. W. Brouwer, A. Baluapuri, S. Habringer, M. Reichert, A. Illendula, O. H. Kramer, M. Schick, E. Wolf, W. F. J. van IJcken, , M. Wirth

The paper identifies RUNX1 inhibition as a strategy to induce NOXA-dependent apoptosis in pancreatic cancer, showing it blocks tumor growth in vivo and in organoids.

bioRxiv · Oct 21, 2021Cancer Biology