Author

I. Fernandez Maestre

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:whole-genome sequencing· 1

Frequent Co-Authors

A. Dunbar· 2 shared A. R. Martinez Benitez· 2 shared L. Cai· 2 shared M. R. Waarts· 2 shared R. L. Bowman· 2 shared R. L. Levine· 2 shared S. E. Eisman· 2 shared S. F. Cai· 2 shared

Activity by Year

2022-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCancer Biology

A. Dunbar

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintMay 18, 2022

Modeling clonal evolution and oncogenic dependency in vivo in the context of hematopoietic transformation

R. L. Bowman, A. Dunbar, T. Mishra…·R. L. Levine

This study models clonal evolution and oncogenic dependency in hematopoietic transformation using reversible mutagenesis and allelic frameworks.

DOI 10.1101/2022.05.18.492524

mousewhole-genome sequencing

𝕏 PostBluesky

Cancer BiologybioRxivPreprintMay 18, 2022

Jak2V617F Reversible Activation Shows an Essential Requirement for Jak2V617F in Myeloproliferative Neoplasms

A. Dunbar, R. L. Bowman, Y. Park…·R. L. Levine

This study shows that reversible activation of Jak2V617F in a mouse model demonstrates its essential role in myeloproliferative neoplasms and highlights the therapeutic potential of mutant-specific JAK2 inhibition.

DOI 10.1101/2022.05.18.492332

mouseexperimental assay

𝕏 PostBluesky