B/T cell crosstalk and aberrant inflammatory IgG exacerbate autoimmune intestinal inflammation
I. Gadjalova, J. M. Heinze, M. C. Goess, J. Hofmann, J. J. Albers, R. Spallek, B. Blissenbach, A. Buck, M.-C. Weber, E. Scherer, M. Kampick, R. Oellinger, O. Krut, R. Rad, K. Steiger, , S. J. Keppler
This study identifies B cell-driven inflammatory mechanisms, including aberrant IgG production and CD86-mediated T cell activation, as contributors to exacerbated intestinal inflammation in IBD.
bioRxiv · Sep 12, 2022 · PreprintImmunology