Author

I. Gomez-Martinez

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Physiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Organism:human· 3 Assay:scRNA-seq· 3 Approach:statistical model· 2 Approach:deep learning· 1 Research Focus:differential expression· 1 Assay:fluorescence / live-cell microscopy· 1

Frequent Co-Authors

K. A. Breau· 3 shared R. J. Bliton· 3 shared S. T. Magness· 3 shared J. Burclaff· 2 shared M. T. Ok· 2 shared A. P. Bhatt· 1 shared C. M. Hinesley· 1 shared E. E. T. San Pedro· 1 shared

Activity by Year

2021-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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3 shared papersCell Biology

K. A. Breau

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

A Leaky Human Colon Model Reveals Uncoupled Apical/Basal Cytotoxicity in Early Clostridioides difficile Toxin Exposure

M. T. Ok, J. Liu, R. J. Bliton, C. M. Hinesley, E. E. T. San Pedro, K. A. Breau, I. Gomez-Martinez, J. Burclaff, S. T. Magness

This study develops a human colon model to assess how C. difficile toxins affect epithelial cells from different sides, finding that basal exposure causes more severe toxicity.

bioRxiv · Oct 13, 2022Cell Biology

Transcriptomics informs design of a planar human enterocyte culture system that reveals metformin enhances fatty acid export

I. Gomez-Martinez, R. J. Bliton, K. A. Breau, M. J. Czerwinski, I. A. Williamson, J. Wen, J. F. Rawls, S. T. Magness

The paper develops a human enterocyte culture system to study lipid handling and finds metformin enhances fatty acid export by promoting fatty acid oxidation.

bioRxiv · Jan 24, 2022 · PreprintCell Biology

A proximal-to-distal survey of healthy adult human small intestine and colon epithelium by single-cell transcriptomics

J. Burclaff, R. J. Bliton, K. A. Breau, M. T. Ok, I. Gomez-Martinez, J. S. Ranek, A. P. Bhatt, J. E. Purvis, J. T. Woosley, S. T. Magness

The paper uses single-cell transcriptomics to analyze healthy adult human small intestine and colon epithelium, identifying lineage markers, regional differences, and functional variations across anatomical regions.

bioRxiv · Oct 5, 2021Physiology