Author

I. L. Pegg

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:imaging· 1

Frequent Co-Authors

A. E. Papathanassiu· 1 shared A. Sarkar· 1 shared C. Mauro· 1 shared C. Tyson· 1 shared C. Yeh· 1 shared D. Lambrechts· 1 shared F. Lodi· 1 shared H. A. Vu· 1 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperImmunology

A. E. Papathanassiu

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2 papers

Recent·Most cited

Video-Microscopy-Based Automated Trajectory Determination for High-Velocity, Densely Clustered, Indistinguishable Objects Moving in A Directed Force Field

C. Tyson, S. Gaire, I. L. Pegg, A. Sarkar

The paper introduces an automated trajectory tracking method for high-velocity, densely clustered, indistinguishable objects in a directed force field, demonstrating its effectiveness through simulations and experimental data.

bioRxiv · Oct 20, 2023 · PreprintBiophysics

BCAT1 inhibition affects CD8+ T cell activation, exhaustion, and tumoral immunity by altering iron homeostasis

F. Lodi, M. Certo, H. Elkafrawy, W. Li, H. A. Vu, K. Gilbo, L. Su, I. L. Pegg, T. Weiss, M. Bühler, M. Weller, C. Yeh, J. E. Corn, K.-S. E. Park, J.-H. Ko, , A. E. Papathanassiu

This study shows BCAT1 inhibition alters iron homeostasis, affecting CD8+ T cell activation, exhaustion, and tumor immunity, with potential as a cancer therapy.

bioRxiv · Feb 25, 2023 · PreprintImmunology