Cancer BiologyCell Chemical BiologyPeer-reviewed
Identification of structurally diverse FSP1 inhibitors that sensitize cancer cells to ferroptosis
J. M. Hendricks, C. Doubravsky, E. Wehri…·J. A. Olzmann
This study identifies structurally diverse FSP1 inhibitors that sensitize cancer cells to ferroptosis, with FSEN1 showing potent on-target inhibition and synergy with ferroptosis inducers.
DOI 10.1016/j.chembiol.2023.04.007