Author

I. M. Ilie

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Biophysics· 2

Signature Assays, Organisms & Methods

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Research Focus:protein folding & dynamics· 3 Approach:experimental assay· 2 Assay:protein structure· 2 Research Focus:cell type annotation· 1 Organism:E. coli· 1 Approach:mechanistic / dynamical model· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

A. Caflisch· 2 shared F. Caporaletti· 2 shared G. Giubertoni· 2 shared S. Woutersen· 2 shared A. Deblais· 1 shared A. Greco· 1 shared A. J. M. Driessen· 1 shared A. Pavan· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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2 shared papersBiophysics

A. Caflisch

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Structural adaptability and surface activity oftardigrade-inspired peptides

G. Giubertoni, S. Chagri, P. G. Argudo, F. Caporaletti, A. Greco, L. Pradel, A. Pavan, I. M. Ilie, Y. Ren, D. Ng, M. Bonn, T. Weil, S. Woutersen

This paper studies model peptides derived from tardigrade proteins to mimic their structural behavior under desiccation, finding they adopt helical structures similar to full proteins.

bioRxiv · Oct 27, 2023 · PreprintBiochemistry

Elucidating the role of water in collagen self assembly by isotopically modulating collagen hydration

G. Giubertoni, L. Feng, K. Klein, G. Giannetti, Y. Choi, A. van der Net, G. Castro-Linares, F. Caporaletti, D. Micha, J. Hunger, A. Deblais, D. Bonn, A. Saric, I. M. Ilie, G. H. Koenderink, S. Woutersen

This study investigates how water isotopes affect collagen self-assembly by comparing D2O and H2O, finding faster assembly and thinner fibrils in D2O due to reduced hydration.

bioRxiv · Jul 31, 2023 · PreprintBiophysics

The role of the first transmembrane helix in bacterial YidC: Insights from the crystal structure and molecular dynamics simulations

K. J. Nass, I. M. Ilie, M. J. Saller, A. J. M. Driessen, A. Caflisch, R. A. Kammerer, X. Li

This study reports the crystal structure of TmYidC and uses MD simulations to show how the TM1 helix enables YidC to switch between insertase and chaperone conformations.

bioRxiv · Jul 15, 2021Biophysics

Thermostable designed ankyrin repeat proteins (DARPins) as building blocks for innovative drugs

J. Schilling, C. Jost, I. M. Ilie, J. Schnabl, O. Buechi, R. S. Eapen, R. Truffer, A. Caflisch, P. Forrer

This paper identifies a mutation that significantly increases thermostability in DARPins, showing its broad applicability and relevance to a clinical drug.

bioRxiv · Apr 27, 2021Biochemistry