Author

I. Malcova

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Assay:imaging· 1 Approach:microscopy & imaging analysis· 1 Assay:proteomics· 1

Frequent Co-Authors

J. Kamanova· 3 shared D. Jurnecka· 1 shared D. Kuzmenko· 1 shared F. Uljanic· 1 shared G. Streparola· 1 shared J. Bayram· 1 shared J. Holubova· 1 shared J. Kucera· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersMicrobiology

J. Kamanova

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Bsp22 protein polymerization drives dynamic adaptation of the Bordetella type III secretion system injectisome

I. Malcova, J. Kamanova

This study investigates Bsp22 protein polymerization in Bordetella species, showing dynamic changes in filament formation during host infection and on abiotic surfaces.

bioRxiv · Mar 4, 2024 · PreprintMicrobiology

Lipid binding by N-terminal motif mediates plasma membrane localization of Bordetella effector protein BteA

I. Malcova, L. Bumba, F. Uljanic, D. Kuzmenko, J. Nedomova, J. Kamanova

This paper identifies the mechanism by which BteA effector protein targets the plasma membrane via its N-terminal LRT domain, showing that lipid binding is not required for cytotoxicity.

bioRxiv · Nov 17, 2020Microbiology

Cytotoxicity of the effector protein BteA was attenuated in Bordetella pertussis by insertion of an alanine residue

J. Bayram, I. Malcova, L. Sinkovec, J. Holubova, G. Streparola, D. Jurnecka, J. Kucera, R. Sedlacek, P. Sebo, J. Kamanova

This paper identifies an alanine insertion at position 503 in B. pertussis BteA that reduces its cytotoxicity compared to B. bronchiseptica BteA, contributing to attenuated virulence and immune response.

PLOS Pathogens · Aug 10, 2020Peer-reviewedMicrobiology