The AAA+ ATPase RavA and its binding partner ViaA modulate E. coli aminoglycoside sensitivity through interaction with the inner membrane
J. Felix, L. Bumba, C. Liesche, A. Fraudeau, F. Rebeille, J. El Khoury, K. Huard, B. Gallet, C. Moriscot, J.-P. Kleman, Y. Duhoo, M. Jessop, E. Kandiah, F. Barras, J. Jouhet, I. Gutsche
This study identifies RavA and ViaA as modulators of E. coli aminoglycoside sensitivity through lipid interactions affecting membrane morphology and antibiotic resistance.
bioRxiv · Feb 6, 2022Microbiology