Author

I. Melero

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 1 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:Arabidopsis· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:cell-cell communication· 1 Assay:DNA methylation· 1 Organism:human· 1 Assay:spatial transcriptomics· 1 Approach:statistical model· 1

Frequent Co-Authors

R. Gonzalez· 2 shared S. F. Elena· 2 shared A. Gomez-Cadenas· 1 shared A. R. Cross· 1 shared C. de Andrea· 1 shared F. Issa· 1 shared G. Ogg· 1 shared I. Roberts· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersMicrobiology

R. Gonzalez

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Within-host virus spreading and tolerance to infection are key factors of the Arabidopsis thaliana age-dependent susceptibility to viral infections

I. Melero, A. Gomez-Cadenas, R. Gonzalez, S. F. Elena

This study investigates age-dependent susceptibility to viral infections in Arabidopsis thaliana, finding that later stages show increased viral spread but also greater fertility, suggesting a trade-off between susceptibility and fitness.

bioRxiv · Nov 21, 2023 · PreprintMicrobiology

Host age-dependent evolution of a plant RNA virus

I. Melero, R. Gonzalez, S. F. Elena

This study investigates how host age affects virus evolution in plants, finding that older hosts lead to faster and more severe infections, with genomic changes varying by host age and viral isolate.

bioRxiv · Jun 28, 2022Evolutionary Biology

Spatial transcriptomic characterization of COVID-19 pneumonitis identifies immune circuits related to tissue injury

A. R. Cross, C. de Andrea, M. Villalba-Esparza, M. Landecho Acha, L. Cerundolo, P. Weeratunga, R. Etherington, L. Denney, G. Ogg, L.-P. Ho, I. Roberts, J. Hester, P. Klenerman, I. Melero, S. Sansom, F. Issa

The paper uses spatial transcriptomics to identify immune circuits in severe COVID-19 lung tissue, finding IFNγ response signatures linked to alveolar damage.

bioRxiv · Jun 21, 2021Immunology