Targeting the deNEDDylating enzyme NEDP1 to ameliorate ALS phenotypes through Stress Granules dissolution
T. Kassouf, R. Shrivastava, I. Meszka, A. Bailly, J. Polanowska, H. Trauchessec, J. Mandrioli, S. Carra, D. Xirodimas
This study shows that inhibiting NEDP1 reduces stress granules and improves cell survival in ALS models.
bioRxiv · Jan 6, 2023 · PreprintCell Biology