Author

I. O. Gordon

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Assay:clinical cohort / trial· 1 Approach:deep learning· 1 Organism:mouse· 1

Frequent Co-Authors

F. Rieder· 2 shared , J. G. Jacqueline G. Perrigoue· 1 shared A. I. Ivanov· 1 shared A. M. Rothemich· 1 shared A. Rogala· 1 shared B. Claggett· 1 shared B. Dogan· 1 shared B. P. Abraham· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersImmunology

F. Rieder

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Stricturing Crohn's disease single-cell RNA sequencing reveals fibroblast heterogeneity and intercellular interactions

P. K. Mukherjee, Q. T. Nguyen, J. Li, S. Zhao, S. M. Christensen, G. A. West, J. Chandra, I. O. Gordon, S. Lin, J. Wang, R. Mao, D. Czarnecki, C. Rayan, P. Kotak, T. Plesec, , F. Rieder

This study uses single-cell RNA sequencing to analyze fibroblast heterogeneity and interactions in Crohn's disease strictures, identifying CDH11 as a potential therapeutic target.

bioRxiv · Apr 3, 2023Immunology

Epithelial cell biomarkers are predictive of response to biologic agents in Crohn's disease

M. Osterman, K. VanDussen, I. O. Gordon, E. M. Davis, K. Li, K. Simpson, M. Ciorba, B. P. Abraham, X. Guo, E. Yee, F. Allard, , J. G. Jacqueline G. Perrigoue, B. Claggett, B. Shen, T. S. Stappenbeck, J. J. Liu

The paper shows that ileal microvillar length (MVL) predicts response to biologics ustekinumab and vedolizumab in Crohn's disease, with combined biomarkers improving prediction accuracy.

bioRxiv · May 20, 2020Cell Biology

Yersiniabactin producing AIEC promote inflammation-associated fibrosis in gnotobiotic Il10-/- mice

M. Ellermann, R. Gharaibeh, L. Fulbright, B. Dogan, L. N. Moore, C. A. Broberg, L. R. Lopez, A. M. Rothemich, J. Herzog, A. Rogala, I. O. Gordon, F. Rieder, C. R. Brouwer, K. W. Simpson, C. Jobin, , J. C. Arthur

The paper shows that Yersiniabactin-producing AIEC bacteria cause inflammation-associated fibrosis in mice, with Ybt import receptor FyuA influencing fibrosis severity.

bioRxiv · Aug 2, 2019Microbiology